Medical Oncologist | Thoracic & Melanoma
Immuno-Oncology | Translational & Real-World Evidence
TIL biology and cross-tumour IO research
CCIT-DK, Copenhagen
Yago Garitaonaindia MD
Also worth considering: are we even measuring the right mechanism?
Some mAbs may derive clinical activity from Fc-mediated effects (as seen with CTLA-4), not just target blockade.
Nice perspective here: ascopubs.org/doi/10.1200/...
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Medical oncologist focused on clinical research, IO and translational science
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Does TIGIT benefit no one…
Or does it benefit a biologically defined subset we failed to identify? 🤔
All-comers trials and conventional biomarkers ignore heterogeneous tumour immune contexts.
Is it time for true precision IO? 🔬
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