GBP1 recruitment to actin-rich pedestals of extracellular Gram-negative bacteria promotes pyroptosis
@avishenoy.bsky.social and colleagues
link.springer.com/article/10.1...
The IFNγ-induced GTPase guanylate-binding protein 1 (GBP1) binds to lipopolysaccharide (LPS) on cytosolic gram-negative bacteria and promotes pyroptosis via the recruitment and activation of caspase-4...