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SLX4IP acts as a genome-wide brake on BLM helicase activity to preserve replication fork stability under stress – both globally and at ALT telomeres Stephanie Panier @spanier55.bsky.social, Kavi Mehta @k4v1.bsky.social and coworkers link.springer.com/article/10.1...
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Faithful DNA replication is essential for genome stability, yet replication forks face constant stress. The Bloom syndrome helicase (BLM) safeguards fork integrity, but excessive BLM activity can itse...
link.springer.com
SLX4IP limits replication stress globally and at ALT telomeres - The EMBO Journal
The EMBO Journal