Which transcription factors control transposable element expression during zygotic genome activation?
Gain-of-function screen by @metorrespadilla.bsky.social and coworkers identifies TBP as direct regulator of mouse endogenous retrovirus-like elements
link.springer.com/article/10.1...
link.springer.com
The activation of the embryonic genome is a crucial step in development. In addition to thousands of genes, many transposable elements (TEs) are robustly transcribed during early mammalian development...
