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These rankings are kinda silly… but hey, we’re #1 🍾🥂🥳
Excited to share Keystone on Neurodevelopmental Disorders in Colorado Jan 2027! ⛷️ with Tom Nowakowski, Stephan Sanders & Joe Zhou 🌟Amazing lineup keynotes from Allyson Berent & Huda Zoghbi! ⏰Abstracts/scholarship due 9/24, Poster abstract due 9/29 Join us: keystonesymposia.org/conferences/...
2mo
4d
Xin Jin
5/7 We then applied Perturb-CLEAR to KO neurodevelopmental disorder genes and found perturbation effects were not uniform: Different genes produced distinct outcomes, with specific vulnerabilities emerging across cell types and across different parts of dendritic architecture
Ardem Patapoutian
2mo
Video
4/7 We mapped how structure changes over time in WT neurons and related those dynamics to RNA programs, revealing coordinated and highly structured remodeling e.g. ASD risk genes were enriched in “stabilizing” program, pointing to an early postnatal window of vulnerability
2mo