Fantastic last seminar before his well deserved retirement by Philippe Reymond @unil.bsky.social on the signaling immune responses following insect cell deposition on plant leaves. A technical tour de force & exciting findings.
Here is our contribution to this lovely special issue.
Together with talented PhD students Gabriel and Mung Hsia, we discussed when and how pattern-triggered immunity had been established in plants.
doi.org/10.1016/j.cu...
@watertoland.bsky.social
@mpipz.bsky.social
TIRs are key regulators of plant immunity, but the role of conserved TIR-only proteins has remained unclear.
Here, we compare TIR-only proteins from Arabidopsis and barley and show that they share a conserved role in plant immunity.
www.biorxiv.org/content/10.6...
Molecular mimicry of a pathogen virulence target by a plant immune receptor | Science www.science.org/doi/10.1126/...
PSA: The Predatory Journal List
#ScienceCrisis
www.predatoryjournals.org/the-list/jou...
📢 new preprint!
How do commensal bacteria establish themselves on plant roots despite plant immunity?
We identify Cpi1, a conserved membrane-anchored protease inhibitor in Pseudomonas that promotes early root colonization and modulates microbial community assembly.
www.biorxiv.org/cgi/content/...
As promised: We have an open 2-year postdoc position in my lab at HHU Düsseldorf, starting September 2026.
Come join us and help pioneering structural biology of fungal GPCRs!
More about the lab: altegoerlab.de
Apply here: karriere.hhu.de/index.php?ac...
Please share with interested candidates!
Michael Hothorn
Toll/interleukin-1/resistance (TIR) domain NADase enzymes signal in plant immunity by producing ribosylated nucleotide second messengers which activate EDS1 dimer-helper NLR pathways to restrict patho...
www.biorxiv.org
Plants and animals respond to pathogen attack by mounting innate immune responses that require intracellular nucleotide-binding leucine-rich repeat (NLR) proteins. These immune receptors detect pathog...
Cool special issue on plant evolution just dropped at @currentbiology.bsky.social our 2 cents:
Fruits of tons of fun discussions with the one and only Susana Coelho:
www.cell.com/current-biol...
Reflections on evolution of auxin response with @jorgehg.bsky.social :
www.cell.com/current-biol...
Host killing by necrotrophs is really complex.
Using a 29-gene knockout series in Botrytis cinerea, we show that removing nearly all known cell death-inducing proteins and major phytotoxins is not sufficient to prevent host necrosis.
Check out the paper: www.biorxiv.org/content/10.6...
We just published our new paper about an active Helitron transposon in wheat 🌾🧬
We found that it can be mobilised by heat stress when DNA methylation is reduced.
We document its full lifecycle: RNA -> circular DNA -> integration
www.nature.com/articles/s41...
#TEsky
Sophien Kamoun
Mauricio Contreras
Our beautiful special issue on plant evolution is out @currentbiology.bsky.social !
www.cell.com/issue/S0960-...
Johana Misas Villamil
Botrytis cinerea is a necrotrophic plant pathogen with an extremely wide host range. During invasion, the fungus induces rapid host cell death and proliferates in the necrotic tissue. The mechanisms o...
Helitrons are a recently identified category of transposons. This study reveals that heat stress combined with reduced DNA methylation can mobilize a Helitron family in wheat. Its mobilization is gene...
We just received funding for a 2yr postdoc position on cryoEM of fungal gpcrs. Official call will open soon.
Contact me if you‘re interested!
Altegoerlab
Der Biologe Dr. Florian Altegoer vom Institut für Mikrobiologie der Heinrich-Heine-Universität Düsseldorf (HHU) erhält einen mit 210.000 Euro dotierten „Exploration Grant“ der Boehringer Ingelheim Stiftung (BIS).
