TIRs are key regulators of plant immunity, but the role of conserved TIR-only proteins has remained unclear.
Here, we compare TIR-only proteins from Arabidopsis and barley and show that they share a conserved role in plant immunity.
www.biorxiv.org/content/10.6...
Toll/interleukin-1/resistance (TIR) domain NADase enzymes signal in plant immunity by producing ribosylated nucleotide second messengers which activate EDS1 dimer-helper NLR pathways to restrict patho...
