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by @danabra.mov
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by @danabra.mov
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by @jimpick.com
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by @atsui.org
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Excited to share a new preprint - We identify a characterize a functional interaction between SLC15A4 and LAMTOR1, providing new insights how this transporter regulates mTOR activation & inflammatory responses downstream of endolysosomal TLRs. Congrats to the team! www.biorxiv.org/content/10.6...
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www.biorxiv.org
Endolysosomal Toll-like receptors (TLRs) 7-9 are critical mediators of antimicrobial immunity, but their dysregulation drives pathogenic inflammation in autoimmune diseases such as systemic lupus eryt...
The SLC15A4-LAMTOR1 interaction licenses endolysosomal TLR-mediated mTOR signaling and inflammatory cytokine production
Chris Parker