Excited to share a new preprint - We identify a characterize a functional interaction between SLC15A4 and LAMTOR1, providing new insights how this transporter regulates mTOR activation & inflammatory responses downstream of endolysosomal TLRs. Congrats to the team! www.biorxiv.org/content/10.6...
www.biorxiv.org
Endolysosomal Toll-like receptors (TLRs) 7-9 are critical mediators of antimicrobial immunity, but their dysregulation drives pathogenic inflammation in autoimmune diseases such as systemic lupus eryt...