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I work on data at Arzeda the protein design company.
Michal Galdzicki









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this is wild - i was aware of Mary-Claire King's absurdly important discoveries on BRCA / inherited breast cancer but I had no idea that her first PhD paper (King & Wilson 1975, Science, not bad lol) is the "99% of protein coding shared btwn chimps and humans" result www.science.org/doi/abs/10.1...
RosettaFold 3 is here! πŸ§¬πŸš€ AtomWorks (the foundational data pipeline powering it) is perhaps the really most exciting part of this release! Congratulations @simonmathis.bsky.social and team!!! ❀️ bioRxiv preprint: www.biorxiv.org/content/10.1...
A summary of the update posted with the announcement x.com/GabriCorso/s...
Boltz-1 update Boltz-1x introduces inference-time steering for much higher physical quality, CUDA kernels for faster, more memory-efficient inference and training. www.biorxiv.org/content/10.1...
BoltzDesign1: Inverting All-Atom Structure Prediction Model for Generalized Biomolecular Binder Design https://www.biorxiv.org/content/10.1101/2025.04.06.647261v1
...where a powerful toy slingshot can be used to mount the LoRa node in a tree for better line-of-sight communications with other devices. www.instructables.com/Meshtastic-S...
πŸš€ Thrilled to share our latest work from Zhang Lab, now published in Science (www.science.org/doi/10.1126/...) We introduce TIGR-Tas, a PAM-free, compact, modular RNA-guided DNA-targeting system in prokaryotes & their viruses. More details coming soon πŸ‘€ #TIGR #RNA #GeneEditing #CRISPR
Sequencing by Expansion (SBX) -- a novel, high-throughput single-molecule sequencing technology https://www.biorxiv.org/content/10.1101/2025.02.19.639056v1
Wait-a-minute 3 in 1 COVID, Flu A, and B tests are already available from Amazon. Is the RSV one coming? I missed the memo. a.co/d/4s5izkO