🧬scCRISPRi screening of 65 Schizophrenia-linked TFs/ERs in iPSC NPCs/neurons to reveal their impact on gene regulatory mechanisms of neurodev!
Happy to been part of the single cell tech dev/analysis of this study lead by @umut_yildiz12 from EMBL/Noh lab! www.biorxiv.org/content/10.1...
SUM-seq is an ultra-high-throughput method for co-profiling chromatin accessibility and gene expression in single nuclei. @anniquec.bsky.social
www.nature.com/articles/s41...
SUM-seq: New single-cell method by @biomedizin.unibas.ch , @embl.org , @au.dk and Tampere university enables large-scale analysis of gene activity & DNA accessibility across millions of cells.
Congrats Prof. Zaugg & collaborators!
🔗 www.nature.com/articles/s41...
Mikael Marttinen
Nature Methods
Department of Biomedicine🔬🧪
www.biorxiv.org
This work presents SUM-seq, an ultra-high-throughput method for co-profiling chromatin accessibility and gene expression in single nuclei across multiplexed samples, advancing the study of gene regula...
