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Moving forward! induced ETX. MGZ: iETX embryos establish a robust anterior signaling center that migrates unilaterally to break embryo symmetry.
16h
The development of mouse embryos can be partially recapitulated by combining embryonic stem cells (ESCs), trophoblast stem cells (TS), and extra-embry…
www.sciencedirect.com
Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro
Yang XF
It takes three to initiate gastrulation. MGZ: Three stem cell types self-assemble in vitro into gastrulating embryo-like structures undertaking spatiotemporal events of the gastrulating mammalian embryo.
17h
Sozen et al. devise an approach to combine embryonic stem cells, trophoblast stem cells and extra-embryonic endoderm stem cells into self-assembling embryo-like structures, which recapitulate key hall...
www.nature.com
Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures - Nature Cell Biology
Yang XF
👍👍👍 Landmark work in the embryo model field. MZG: establishing a close cross-talk between emb and exe in a 3D ECM scaffold is necessary and sufficient for the self-assembly.
17h
Embryonic and trophoblast stem cells self-assemble to generate a structure resembling a natural mouse embryo.
www.science.org
Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro
Yang XF