It takes three to initiate gastrulation. MGZ: Three stem cell types self-assemble in vitro into gastrulating embryo-like structures undertaking spatiotemporal events of the gastrulating mammalian embryo.
Sozen et al. devise an approach to combine embryonic stem cells, trophoblast stem cells and extra-embryonic endoderm stem cells into self-assembling embryo-like structures, which recapitulate key hall...
👍👍👍 Landmark work in the embryo model field. MZG: establishing a close cross-talk between emb and exe in a 3D ECM scaffold is necessary and sufficient for the self-assembly.
Embryonic and trophoblast stem cells self-assemble to generate a structure resembling a natural mouse embryo.
