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👍👍👍 Landmark work in the embryo model field. MZG: establishing a close cross-talk between emb and exe in a 3D ECM scaffold is necessary and sufficient for the self-assembly.
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Embryonic and trophoblast stem cells self-assemble to generate a structure resembling a natural mouse embryo.
www.science.org
Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro
Yang XF