How does metabolic dependency evolve at the single cell level? 🔄
In our new preprint, Divvya Ramesh combines microfluidics, microscopy and modelling to show that the benefits of gene loss are highly context dependent.
Check it out here: www.biorxiv.org/content/10.1...
www.biorxiv.org
Also excited to share our latest collaboration with @micsysecolab.bsky.social. Divvya Ramesh showed how spatial structure can limit evolution of metabolic dependencies.
We have an open position for a bioinformatics/theoretical microbial ecology PhD student to study viral strategies in the global Microverse! Join us at the @microverse.bsky.social at @uni-jena.de, please apply through this link:
jobs.uni-jena.de/jobposting/9...
Microbial Systems Ecology Lab
Wrapping up a productive week: very glad to have contributed to this review on how spatial structure shapes microbial ecology and evolution, led by @marcelbaecker.bsky.social, @bedutilh.bsky.social, @bramvandijk.bsky.social and many others. doi.org/10.1093/fems...
Excited to share first preprint from our lab! @giubotti.bsky.social found that antibiotic tolerance in multispecies biofilms follows a surprising spatial pattern: cells survive only at intermediate distances from a partner species. 🦠 Preprint: doi.org/10.64898/202...
New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...
Spatial structure naturally emerges in microbial communities, shaping growth, interactions, and evolution, and revealing how microscale processes scale up
Excited to finally share the typeset version of our very first venture into microbial ecology! 🤩
Big thanks to @simonvanvliet.bsky.social for a rewarding collaboration within the NCCR Microbiomes.
@fbm-unil.bsky.social
@dmf-unil.bsky.social
Excited to share our new paper led by Divvya Ramesh: Limits to the evolution of metabolic dependency in spatially structured microbial communities 🧫
www.sciencedirect.com/science/arti...
Huge thanks to our amazing collaborators in @nccr-antiresist.bsky.social and NCCR Microbiomes!
Using a quantitative framework we show that this pattern emerges from the combined effect of two opposing interactions with different ranges. As a result, spatial arrangement determines overall tolerance by balancing the relative importance of these interactions.
Simon van Vliet
Simon van Vliet
Simon van Vliet
In microbial communities, evolutionary processes can lead to loss of biosynthetic pathways, creating metabolic dependencies. The Black Queen Hypothesi…
Most microbes don't live in shaking flasks; spatial structure shapes how microbes interact and evolve at every scale, as we discuss in our recent review @jeroenmeijer.bsky.social @simonvanvliet.bsky.social @bedutilh.bsky.social @bramvandijk.bsky.social and others
academic.oup.com/femsre/artic... 🧵👇
