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Junior Group Leader @ Biozentrum-UniBasel & DMF-UNIL Physicist turned biologist | Ecology & evolution of complex systems | Emergent behavior in microbial systems vanvlietlab.ch
Simon van Vliet









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4mo
How does metabolic dependency evolve at the single cell level? 🔄 In our new preprint, Divvya Ramesh combines microfluidics, microscopy and modelling to show that the benefits of gene loss are highly context dependent. Check it out here: www.biorxiv.org/content/10.1...
Excited to share first preprint from our lab! @giubotti.bsky.social found that antibiotic tolerance in multispecies biofilms follows a surprising spatial pattern: cells survive only at intermediate distances from a partner species. 🦠 Preprint: doi.org/10.64898/202...
May 13, 2025
Excited to finally share the typeset version of our very first venture into microbial ecology! 🤩 Big thanks to @simonvanvliet.bsky.social for a rewarding collaboration within the NCCR Microbiomes. @fbm-unil.bsky.social @dmf-unil.bsky.social
We have an open position for a bioinformatics/theoretical microbial ecology PhD student to study viral strategies in the global Microverse! Join us at the @microverse.bsky.social at @uni-jena.de, please apply through this link: jobs.uni-jena.de/jobposting/9...
Simon van Vliet
Most microbes don't live in shaking flasks; spatial structure shapes how microbes interact and evolve at every scale, as we discuss in our recent review @jeroenmeijer.bsky.social @simonvanvliet.bsky.social @bedutilh.bsky.social @bramvandijk.bsky.social and others academic.oup.com/femsre/artic... 🧵👇
Using a quantitative framework we show that this pattern emerges from the combined effect of two opposing interactions with different ranges. As a result, spatial arrangement determines overall tolerance by balancing the relative importance of these interactions.
9mo
Also excited to share our latest collaboration with @micsysecolab.bsky.social. Divvya Ramesh showed how spatial structure can limit evolution of metabolic dependencies.
Huge thanks to our amazing collaborators in @nccr-antiresist.bsky.social and NCCR Microbiomes!
4mo
3mo
4mo
4mo
4mo
www.biorxiv.org
Wrapping up a productive week: very glad to have contributed to this review on how spatial structure shapes microbial ecology and evolution, led by @marcelbaecker.bsky.social, @bedutilh.bsky.social, @bramvandijk.bsky.social and many others. doi.org/10.1093/fems...
Microbial Systems Ecology Lab