Today is #WorldOceanDay 🌊
Oceans are home to more than 200,000 marine species. 🐢🐬🐋🦈
Did you know marine invertebrates produce more antibiotics, anti-cancer, and anti-inflammatory substances than any group of terrestrial organisms? 👀
Read more📲: https://ow.ly/weuM50Z7G1x
Volgens socioloog Ulrich Beck raakt de behoefte aan welvaart verzadigd. Daardoor groeit de aandacht voor de gevaren die de toegenomen rijkdom veroorzaakt.
Two new activities for #barettin, extracted from my pet sponge 'Geodia barretti' : promising activity against 1) chronic pain and 2) the most common and aggressive type of pancreatic cancer! Two papers from the Cartmell Lab👇
www.mdpi.com/1660-3397/24...
doi.org/10.1021/acs....
Despite increasing interest, there remain limited treatments for chronic pain, with opioids continuing to be one of the top prescribed medications. Marine natural products present a wealth of untapped potential for new treatments for chronic pain. In this study, we investigated the analgesic effects of the sea sponge ligand barettin in a mouse model of chemotherapy-induced peripheral neuropathy (CIPN). Barettin exhibited efficacious antihyperalgesic activity in male mice with no efficacy shown in females. Through the use of a PRESTO-Tango assay, we found that barettin acts as an inverse agonist at the 5HT2A receptor while also presenting no activity at the μ-opioid receptor. Head twitch experiments confirmed no hallucinogenic activity, suggesting that barettin may be a promising nonopioid, nonhallucinogenic, marine-derived therapeutic agent for the treatment of chronic pain.
Ik snap wel dat ze ontstemd zijn. Misschien iets meer dan dat. Eerst decennia aan het Lelylijntje gehouden en dan nu de wegen in het noorden even op het 2e plan....
National Wildlife Federation
outer membrane vesicles (OMVs) of 𝘝𝘪𝘣𝘳𝘪𝘰 𝘧𝘪𝘴𝘤𝘩𝘦𝘳𝘪 are apparently piñatas full of goodies for its host, 𝘌. 𝘴𝘤𝘰𝘭𝘰𝘱𝘦𝘴.
earlier we featured SsrA (tmRNA), now comes SypC protein - both required for proper ldevelopment of the squid's light organ.
#SymbioSky
Paco Cardenas
NRC
The genetic repertoire of deep-sea #microbiome:
From sequence to structure and function
www.sciencedirect.com/science/arti... #OpenAccess #microbiota #marine #deepsea #AI #environment #MicroSky
Our new paper „Variations in the latitudinal diversity gradients of the ocean microbiome“ was just published in @cp-cellhostmicrobe.bsky.social 🥳
We present a global analysis of prokaryotic #biodiversity in the surface and mesopelagic layers of the ocean 🦠🌊
www.cell.com/cell-host-mi...
Eriksson et al. conduct a global marine microbiome diversity analysis and demonstrate
how the surface ocean latitudinal diversity gradient is disproportionately shaped
by a few species-rich taxa. Mask...
www.cell.com
by Janie — This New Year story begins with newly hatched baby bobtail squids. Each squid is translucent and barely the size of a grain of barley. As they swim around, the six pores on their heads …
Happy World Ocean Day! May we all continue to understand our oceans better so that we can protect and preserve them better.
Sarah Hird, PhD
Scientists surveying the area found three times more #seabed organisms and twice as many species compared to nearby unprotected waters. goodmenproject.com/featured-con...
STCmicrobeblog
Scientists surveying the area found three times more seabed organisms and twice as many species compared to nearby unprotected waters.
Volgens socioloog Ulrich Beck raakt de behoefte aan welvaart verzadigd. Daardoor groeit de aandacht voor de gevaren die de toegenomen rijkdom veroorzaakt.
There are almost no crustaceans in the deep ocean.
Not because they would get crushed, but because they would DISSOLVE.
The cold & high pressure cause changes to water that make it very corrosive to calcium carbonate shells.
But there's one crustacean who solves this problem with ALUMINUM ARMOR.
