Fascinating temperature effect on gene expression during conidiophore development in the pulmonary pathogen Aspergilus fumigatus suggesting perhaps that conidia are primed for parasexual or sexual development to enhance chances of survival under extreme conditions. From @mcmomany.bsky.social 👇
Nick Talbot
Big surprise just out from our lab. Transcriptome from A. fumigatus conidiophore made at 50C is upregulated for MAT1-1. Why is this sexual master regulator up in asexual development? Maybe priming future progeny for survival?
www.biorxiv.org/content/10.6...
Aspergillus fumigatus is a thermotolerant saprobe found in soils and plant debris worldwide and an important pathogen of humans causing two million deaths annually. A. fumigatus makes abundant asexual...
