Fungal Biologist studying Aspergillus fumigatus, Aspergillus nidulans, antifungal resistance, septin cytoskeleton, septin evolution, and spore dormancy. Views expressed here are my own.
Michelle Momany
Big surprise just out from our lab. Transcriptome from A. fumigatus conidiophore made at 50C is upregulated for MAT1-1. Why is this sexual master regulator up in asexual development? Maybe priming future progeny for survival?
www.biorxiv.org/content/10.6...
Related: if you know a great undergrad interested in grad school (or if YOU are interested), & they'd like to work in fungal biology using population genomics to study pathogenicity and genome plasticity, please encourage them to reach out!
See annehatmaker.com/contact/ for more info on how
It is no surprise that contamination leads to incorrect conclusions in population genetics studies. @audreykward.bsky.social, @mcmomany.bsky.social, @dbensasson.bsky.social caution that even low-level contamination has a greater impact on analyses than expected.
More in #G3journal: buff.ly/kYFXQfM
Aspergillus fumigatus is a thermotolerant saprobe found in soils and plant debris worldwide and an important pathogen of humans causing two million deaths annually. A. fumigatus makes abundant asexual...
Antifungal resistance is growing – will new treatments turn the tables? www.nature.com/articles/d41...
Michelle Momany
Peer-reviewed version of our study led by @aliceeseola.bsky.social first seen on @biorxiv-cellbio.bsky.social showing the exquisite level of control of organelle trafficking & autophagy exerted during plant infection by the blast fungus. Thanks to all co-authors.
www.cell.com/cell-reports...
Annie Hatmaker, Ph.D.
Really grateful to all co-authors who made this possible 🙏
Neha Sahu @mariselagarduno.bsky.social Paul Derbyshire @frankmenke.bsky.social Weibin Ma @talbotlabtsl.bsky.social
Happy to hear any thoughts or feedback! 🌱🍄
Trials of drugs to fight deadly resistant infections are advancing, but they might fall victim to overuse of agricultural fungicides just like their predecessors.
I shared on LinkedIn already, but I wanted to post here as well since I've got a different audience: I will be joining the Department of Plant Pathology at the @universityofga.bsky.social as an Assistant Professor on Aug 1!! I will keep studying #Aspergillus & #Fusarium that infect plants & humans 🥰
Genetics Society of America
The blast fungus forms a force-generating appressorium for plant infection. Eseola
et al. show how individual spore cells adopt distinct fates, trafficking organelles
to the appressorium or undergoing...
A new study from our group, led by Iris Eisermann, of the septin interactome during appressorium development, revealing many new interactors and significantly widening the biological function of septins in fungal pathogenesis. 👇
@thesainsburylab.bsky.social
So proud to see this story finally out!🎉 We added new data since our previous preprint—transgenic barley plants with an engineered immune receptor that fights off two fungal pathogens at once. Short 🧵 and link to the original preprint thread on X👇
www.science.org/doi/10.1126/...
The X-linked Septin6 strikes in the immune system!
Neil Gow
Our newest review on septins as makers & breakers of membrane contacts in J Neurochem
Fun writing with new PhD grad (and FASEB Septin Conference A/V Assistant Extrordinaire) TJ Holt
Thanks @mcmurraylab.bsky.social @sergemostowylab.bsky.social for input.
onlinelibrary.wiley.com/doi/10.1111/...
Iris Eisermann
Nick Talbot
Annie Hatmaker, Ph.D.
Plants and animals respond to pathogen attack by mounting innate immune responses that require intracellular nucleotide-binding leucine-rich repeat (NLR) proteins. These immune receptors detect pathog...
Septins are a family of GTP-binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. G...
