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THIS IS AN IMPORTANT PAPER FOR TRANSLATIONAL-CIRCUIT-BASED THERAPEUTICS Circuit-specific gene therapy reverses core symptoms in a primate Parkinson’s disease model: Cell www.cell.com/cell/fulltex...
An AAV-based circuit modulation approach that consists of a designer retrograde AAV capsid, a medium spiny neuron-enriched promoter, and a selected chemogenetic effector specifically modulates direct ...
www.cell.com
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Circuit-specific gene therapy reverses core symptoms in a primate Parkinson’s disease model
Bryan Roth