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#gpcr Dimers! Here, we demonstrate stable κOR dimer formation in living cells ... revealing a parallel assembly distinct from previously characterized GPCR dimers that engage only single G protein. pubmed.ncbi.nlm.nih.gov/42215488/
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pubmed.ncbi.nlm.nih.gov
The κ-opioid receptor (κOR) represents a promising non-addictive analgesic target due to its critical role in pain and reward pathways. Despite evidence of κOR dimerization, its molecular basis and ph...
Structural characterization of kappa-opioid receptor dimer in complex with two G proteins - PubMed
Bryan Roth