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HHMI Freeman Hrabowski Scholar and Assistant Professor in the Department of Microbiology at the University of Washington studying host-pathogen interactions in beautiful Seattle. (he/him). Opinions are my own and do not reflect those of my employer.
Patrick S. Mitchell









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Of all the harm this administration has done to US science, today's proposed changes to the way federal grants are awarded and administered is the most damaging yet. The text of the federal register document is impenetrably tedious by design, so here's an excellent summary of what it says.
12d
Very excited to be invited to this exciting meeting! See you in France in a few short months!
4mo
I'm excited to announce our new biorxiv preprint, wherein we investigate the evolution of the weirdest genetic locus I've ever seen! Behold the tgr genes of the social amoeba, which mediate self/non-self discrimination during facultative multicellularity 🐅 🧵 1/ www.biorxiv.org/content/10.1...
Carl T. Bergstrom
The University of Washington Department of Microbiology seeks to hire an Assistant Professor, Tenure Track. apply.interfolio.com/185622 We're interested in mechanistic approaches to study physiology and/or pathogenesis of bacteria and viruses, as well as microbial community interactions.
What does 18,000+ brave signatories look like standing together in massive solidarity with the #NIH heroes of the historic Bethesda Declaration??... Find out by adding YOUR NAME to our #NIHLove letter here! - actionnetwork.org/forms/add-na... #StandUpForScience #BethesdaDeclaration #StopTrump
You asked, we answered — this time for our united #FreemanHrabowski Scholars and #HannaGray Fellows programs. A warm welcome into who's eligible, how the programs connect, and more, from our very own Science Program team members Mary Bonds & Lucy Corcoran. Applications open 11/3! bit.ly/fhs26 🧪
10mo
Patrick S. Mitchell
Check out our new publication, a collaboration with Giovanni Luchetti and Vishva Dixit @ Genentech. We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!! www.nature.com/articles/s41... Explainer 1/8
Over 70K in Seattle denounce Trump at massive ‘No Kings’ rally
Co-discoverer of reverse transcriptase at 32, Nobel Prize at 37, played a key role at the 1975 Asilomar comference.
13d
Thrilled to announce that the Department of Microbiology at the University of Washington, School of Medicine is hiring at the Assistant Professor level (tenure-track)! The Pacific Northwest is an awesome place to live and do science 🧪🦠. Join us! apply.interfolio.com/185622 Applications due 8/1.
Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule. Russell Vought is going destroy American Science. elizabethginexi.substack.com/p/summary-of...
Jun 11, 2025
15d
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Cells require highly polymorphic receptors to perform accurate self/non-self recognition. In the amoeba Dicytostelium discoideum, polymorphic TgrB1 & TgrC1 proteins are used to bind sister cells and e...
www.biorxiv.org
Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes in Dictyostelium
7mo
Jun 14, 2025
9mo
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
16d
12d
actionnetwork.org
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Tera Levin
Registration deadline is fast approaching for the "Host adaptations to viral infections” Meeting May 10th-13th, 2026, at the CNRS Station Biologique de Roscoff, Brittany, France! JOIN US and the many amazing speakers! JOIN US! sites.google.com/berkeley.edu...
Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion - Nature
The bacterial ubiquitin ligase NleL evades host defence mechanisms both by inhibiting pyroptosis and by preventing infected intestinal epithelial cells from being extruded into the lumen and expelled ...
www.nature.com
Massive crowds gathered in Cal Anderson Park, aboard a state ferry and at the state Capitol to denounce the hard-line policies of President Donald Trump.
www.seattletimes.com
Over 70K in Seattle denounce Trump at massive ‘No Kings’ rally
www.nytimes.com
David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
Russell Vought is going destroy American Science
elizabethginexi.substack.com
Summary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule
Stand Up for Science!
Alex Merz 🇺🇸🇨🇦🇺🇦
HHMI
4mo
Patrick S. Mitchell