we got the cover!!! Novel light-driven schizorhodopsins from Antarctic Minisyncoccota (Patescibacteria) and cyanobacteria www.sciencedirect.com/science/arti...
Transient absorption spectroscopy on Channelrhodopsin-1 by Prof. Heberle's group. A red-shifted intermediate was revealed to correspond to the channel-open state. Congratulations!!🎉✨
www.sciencedirect.com/science/arti...
Our collaborative work with Prof. Kawamura (YNU) on solid-state NMR of the inward proton-pumping rhodopsin, schizorhodopsin is now in Biophys. Chem.!📄✨80% of residues were assigned, revealing secondary structure and protonation states of key residues!🥳
www.sciencedirect.com/science/arti...
As of today, the Inoue Lab has moved from ISSP, Univ. Tokyo, to the Department of Integrated Biosciences, Graduate School of Frontier Sciences, Univ. Tokyo🏢✨We will continue advancing our rhodopsin research! 🧪🧬 Furthermore, we will remain active at ISSP through a cross-appointment 🍀
Cryo-EM structure of the SRI-HtrI complex by Prof. Chii-Shen Yang's group. Congratulations!✨
www.nature.com/articles/s41...
@natcomms.nature.com #OpenAccess
A new study on the excited-state dynamics of Archaerhodopsin-3 (AR3) has been published in Biophys. J.🥳Spectroscopy and calculation revealed that protonation of the retinal counterion prolongs the excited-state lifetime and enhances fluorescence✨
www.cell.com/biophysj/ful...
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Time-resolved resonance Raman spectroscopy of sodium-pumping rhodopsin, KR2, by Prof. Peter Hildebrandt's group.
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
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Resurrecting Full-Length Ancestral Schizorhodopsins and Heliorhodopsins with Structure-Guided, Indel-Aware Sequence Reconstruction by Prof. Mizutani & Prof. Ishikawa. Congratulations!🎉
pubs.acs.org/doi/10.1021/...
PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness and photostability🌸
www.nature.com/articles/s41...
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Channelrhodopsins (ChRs) are light-controlled ion channels that have become indispensable tools in the field of optogenetics. Channelrhodopsin-1 from …
Archaerhodopsin-3 (AR-3) and its mutants have attracted a large attention for applications
in optogenetics since they display a voltage-sensitive, near-infrared fluorescence.
Recent quantum chemistry ...
www.cell.com
The microbial retinal protein KR2 (Krokinobacter eikastus) is a light-driven outward Na+ pump, which is coupled to the photocycle of the chromophore. Using time-resolved continuous-wave pump-probe re...
Microbial rhodopsins exhibit diverse functions ranging from ion pumps and channels to light sensors, despite sharing a common seven-transmembrane (7TM) architecture. Understanding how this functional ...
pubs.acs.org
PinkyCaMP is a red genetically encoded calcium indicator with improved brightness and photostability. Derived from mScarlet, it does not exhibit photoswitching upon blue light illumination and is ther...