we got the cover!!! Novel light-driven schizorhodopsins from Antarctic Minisyncoccota (Patescibacteria) and cyanobacteria www.sciencedirect.com/science/arti...
PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness and photostability🌸
www.nature.com/articles/s41...
@natchem.nature.com #OpenAccess
INOUE lab. (ISSP, Univ. Tokyo)
BejaLab
Our collaborative work with Prof. Kawamura (YNU) on solid-state NMR of the inward proton-pumping rhodopsin, schizorhodopsin is now in Biophys. Chem.!📄✨80% of residues were assigned, revealing secondary structure and protonation states of key residues!🥳
www.sciencedirect.com/science/arti...
As of today, the Inoue Lab has moved from ISSP, Univ. Tokyo, to the Department of Integrated Biosciences, Graduate School of Frontier Sciences, Univ. Tokyo🏢✨We will continue advancing our rhodopsin research! 🧪🧬 Furthermore, we will remain active at ISSP through a cross-appointment 🍀
Cryo-EM structure of the SRI-HtrI complex by Prof. Chii-Shen Yang's group. Congratulations!✨
www.nature.com/articles/s41...
@natcomms.nature.com #OpenAccess
A new study on the excited-state dynamics of Archaerhodopsin-3 (AR3) has been published in Biophys. J.🥳Spectroscopy and calculation revealed that protonation of the retinal counterion prolongs the excited-state lifetime and enhances fluorescence✨
www.cell.com/biophysj/ful...
@biophysj.bsky.social
Time-resolved resonance Raman spectroscopy of sodium-pumping rhodopsin, KR2, by Prof. Peter Hildebrandt's group.
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#OpenAccess
Transient absorption spectroscopy on Channelrhodopsin-1 by Prof. Heberle's group. A red-shifted intermediate was revealed to correspond to the channel-open state. Congratulations!!🎉✨
www.sciencedirect.com/science/arti...
Resurrecting Full-Length Ancestral Schizorhodopsins and Heliorhodopsins with Structure-Guided, Indel-Aware Sequence Reconstruction by Prof. Mizutani & Prof. Ishikawa. Congratulations!🎉
pubs.acs.org/doi/10.1021/...
INOUE lab. (ISSP, Univ. Tokyo)
INOUE lab. (ISSP, Univ. Tokyo)
INOUE lab. (ISSP, Univ. Tokyo)
Microbial rhodopsins exhibit diverse functions ranging from ion pumps and channels to light sensors, despite sharing a common seven-transmembrane (7TM) architecture. Understanding how this functional ...
PinkyCaMP is a red genetically encoded calcium indicator with improved brightness and photostability. Derived from mScarlet, it does not exhibit photoswitching upon blue light illumination and is ther...
Archaerhodopsin-3 (AR-3) and its mutants have attracted a large attention for applications
in optogenetics since they display a voltage-sensitive, near-infrared fluorescence.
Recent quantum chemistry ...
The microbial retinal protein KR2 (Krokinobacter eikastus) is a light-driven outward Na+ pump, which is coupled to the photocycle of the chromophore. Using time-resolved continuous-wave pump-probe re...
Channelrhodopsins (ChRs) are light-controlled ion channels that have become indispensable tools in the field of optogenetics. Channelrhodopsin-1 from …
