Very happy that our manuscript with my brilliant collaborators @jamestrujillo.bsky.social and @straubeb.bsky.social is now published @jneurolang.bsky.social. 🥳🥳🥳 Interested in gesture, discourse, fMRI, prediction, computational modeling? This is the paper for you 👇 doi.org/10.1162/NOL....
New paper in Scientific Reports: Using HRF temporal and dispersion derivatives, we show altered preparatory neural timing in SSD, particularly during self-generated action processing. www.nature.com/articles/s41...
#Schizophrenia #fMRI #SenseOfAgency
We're looking for a student assisten (HIWI) in the TNM Lab!!! www.uni-marburg.de/de/universit...
#PuG2026 was a fantastic conference! Now you can already safely the date for #PuG2027 in Oldenburg: 6-8 May, 2027! 🧠
Toller Artikel @zeit.de über Placebo-Effekte @sfb-trr-289.bsky.social. Toll auf den Punkt gebracht, dass der Placebo-Effekt ein klinisch extremlich nützlicher Mechanismus ist, der von Medizin und Pharma als Freund, nicht als Feind, betrachtet werden sollte. www.zeit.de/gesundheit/2...
New manuscript:
From Expectation to Learning: A Mediational Model of Exposure Therapy Outcome in Anxiety Disorders
We propose a hierarchical pathway: generalized expectations → treatment-specific expectations → learning rate during exposure → clinical outcome. doi.org/10.1159/0005...
#Expectation
Our special issue on the CRC/TRR 393 "Trajectories of Affective Disorders" is out. Find out all about the project here
www.springermedizin.de/der-nervenar...
@trr393.bsky.social @tudresden.bsky.social @uni-muenster.de @unimarburg.bsky.social
Why are tactile sensations suppressed during movements? In our new preprint, we explain this as optimal integration of sensory signals with an internal model.
Work led by @fatatai.bsky.social with Dimitris Voudouris, Katja Fiehler and @c-rothkopf.bsky.social
www.biorxiv.org/content/10.6...
How is genetic risk for inflammation linked to mental disorders?
Our new study applies transdiagnostic network analysis to uncover symptom-level associations beyond categorical diagnoses. www.sciencedirect.com/science/arti...
Scientific Reports - Disrupted neural response timing and duration during hand movement preparation in schizophrenia spectrum disorder: An fMRI study
www.nature.com
Wir haben eine Apotheke in uns, die wir kostenlos nutzen können. Der Placebo-Effekt ist so stark, dass wir eigentlich das gesamte Gesundheitswesen umkrempeln müssten.
Abstract. Introduction: Negative expectations about treatment outcomes are associated with poorer recovery in anxiety disorders. However, it remains unclear whether (1) patients’ expectations about how effective the treatment will be (treatment-specific expectations) mediate the link between generalized negative expectations (i.e. unspecific pessimistic beliefs) and treatment outcomes, and (2) these expectations affect outcomes via the learning rate during exposure therapy, that is, the extent to which patients update their fear-related beliefs based on corrective experiences. Since treatment-specific expectations may be more modifiable, clarifying these mechanisms could improve interventions. This study investigated whether treatment-specific expectations and learning rate mediate the effect of generalized negative expectations on treatment outcomes. Methods: Data from 605 patients with various anxiety disorders undergoing 12 sessions of manualized exposure therapy were analyzed. Generalized negative expectations at baseline (session 0) were hypothesized to predict treatment outcomes (i.e., symptom severity at post treatment) via expectations about treatment success measured at session 4 and learning rate during exposure. Depression and anxiety at baseline were covariates. Mediation analyses were conducted using the PROCESS macro with bootstrap confidence intervals. Results: Generalized negative expectations predicted poorer treatment outcomes (higher symptom severity), mediated by lower expectations about treatment success (β = 0.0375; 95% CI: 0.0088–0.0730). A sequential mediation via these treatment-specific expectations and learning rate was also significant (β = 0.0059; 95% CI: 0.0008–0.0134), even after accounting for baseline symptom levels (R² = 0.3375). Conclusion: Targeting both generalized and treatment-specific expectations early in treatment may enhance exposure-based learning and improve clinical outcomes in anxiety disorders.
Abstract. Understanding one another in daily communication depends on predicting language from prior discourse context and visual signals, such as co-speech gestures. However, it remains unclear how d...
doi.org
Although low-grade inflammatory processes have traditionally been studied in affective disorders, they are increasingly recognized as relevant across …
Deadline extended to the 17.05.2026: www.uni-marburg.de/de/universit...
TNM-Lab
When listening to a story, earlier parts of the story (context) and the speaker's gestures help us predict and understand what they are saying. In a new preprint we show context and gestures have a push-pull synergy on neural response to linguistic information 👇🧵
Why is touch perceived as weaker during movement?
In our new preprint 📝, we examine tactile suppression during reaching.
Using optimal control theory, we show that tactile suppression reflects dynamic, uncertainty-dependent integration of forward model predictions and sensory feedback.
