In #GENETICS, @jazlynmooney.bsky.social and the team present a unified theoretical framework for understanding how recombination shapes ancestry patterns after admixture.
🔗 buff.ly/7i4EFAc
🚀 We are introducing PerturbPair (with Taka Kudo) — a platform that combines parallel Perturb-seq and optical pooled screening (PerturbView) in primary cells to systematically map at massive scale how genetic perturbations reshape cellular states across modalities.
www.biorxiv.org/content/10.6...
Genetics Society of America
got my concluding slide on challenges with estimating ancestral recombination graphs ready for PEQG
postdoc alert 🚨! NIH-funded postdoc in my lab to work on Ancestral Recombination Graphs in space. Please spread the word widely in your networks, and please reach out if you're interested! (2-3yr position, start date flexible, pay/benefits good!).
details here: careers.umich.edu/job_detail/2...
We built a joint experimental and computational platform for scalable multi-modal single-cell chemical screens — profiling RNA, protein (including phospho-signaling), and chromatin accessibility responses to thousands of small molecule perturbations in parallel. www.biorxiv.org/content/10.6...
The 2026 Genomic History Inference Strategies Tournament is live! ghist.bio
Today was the kickoff tutorial at the Modeling and Theory in Population Biology workshop at @icerm.bsky.social . Looking forward to summer workshops at PEQG @genetics-gsa.bsky.social and at SMBE @official-smbe.bsky.social .
Multiple positions available: ​ Postdoc PhD students
Check out our new paper presenting pg-gpu, a GPU-accelerated population genetics python package:
www.biorxiv.org/content/10.6... 1/3
Ryan Gutenkunst
Jeffrey Ross-Ibarra
Come see my poster tn! For 3 yrs, populations evolved at 43 sites worldwide. I built kMate, an alignment-free, pangenome k-mer method to track SNP & SV frequencies across space & time, opening the door to accurately and efficiently mapping climate-adaptive variants on evolution experiments! #PEQG26
www.biorxiv.org
JIT 4 summer, the latest preprint from our lab, brilliantly led by @kaitezhang.bsky.social w/ support from Collepardo lab (@juliamaristany.bsky.social / @janhuemar.bsky.social). www.biorxiv.org/content/10.6... describes a new single-molecule epigenomic method, & discoveries it enables ... (1/n)
Nucleosome spacing influences higher-order chromatin fiber organization in vitro but how this relates to cellular chromosome structure remains contentious. To address this, we developed Ligation Analy...
#PEQG26 folks! I will be presenting my postdoc project with @jkpritch.bsky.social and @jeffspence.github.io about inferring population structure dynamics over time with tensor decomposition on ARG. The talk will be at the James Crow Talk session on Wednesday. Look forward to seeing everyone there!
