We fund cutting-edge scientific research across multiple Branches and Centers to better understand cancer and eliminate the suffering caused by the disease.
Ludwig Cancer Research
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Check out this video with Ludwig @ox.ac.uk’s Xin Lu on the @cancergrand.bsky.social Team ATLAS’s goal to find biomarkers—antibody fingerprints—that predict whether someone might avoid or, conversely, develop cancer and possibly identify treatments for cancer prevention or therapy.
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Congratulations to Ludwig @unil.bsky.social’s @johannajoyce.bsky.social, who began her two-year term today as president of the European Association for Cancer Research @helloeacr.bsky.social.
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Congratulations to Ludwig @ox.ac.uk’s Emily Steffke, who just earned her PhD! Pictured here at #AACR2026 with her poster and her advisors Ludwig’s Benoit Van den Eynde and Masaki Terabe of the NCI, with whom she has been developing a viral vector-based vaccine for the treatment of glioblastoma.
Ludwig @harvard.edu’s @tanjinakader.bsky.social of the Santagata lab at #AACR2026, where she presented her research titled “Integrative spatial profiling of protein and chromosomal alterations across normal, precancer, and cancer revealed the presence of aneuploidy in the normal fallopian tube.”
Ludwig @harvard.edu’s Na Zhang of the Brown lab discusses the findings presented in her poster “ELF3-driven epigenetic reprogramming creates ERK pathway dependency in SERD-resistant ER+ breast cancer” with an interested attendee at #AACR2026.
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Ludwig @harvard.edu’s Benjamin Wolf of the Jain lab presented at #AACR2026 his findings from preclinical studies showing how chronic high blood pressure reprograms the anti-tumor immune response in pancreatic tumors, explaining why a type of antihypertensive drug improves treatment of such patients.
Ludwig @harvard.edu’s @kenichi-shimada.bsky.social of the @jguerriero.bsky.social lab explains his findings at #AACR2026 showing that a combination therapy tested in the TALAVE trial altered the immune landscape of breast tumors depending on the presence of a mutant BRCA gene.
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Ludwig @harvard.edu’s Heena Kumra of the Jain lab presented her research at #AACR2026 in a poster titled: “Improving response of pancreatic cancer to losartan: Mechanistic insights and implications for personalized therapy.”
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Ludwig @princeton.edu's Eileen White, a co-leader of the Cancer Grand Challenges CANCAN team, spoke at #AACR2026 about the team’s findings on cachexia, including how it causes metabolic dysfunction that may contribute to depression and amotivation, exacerbating the cancer-associated wasting syndrome
Ludwig @harvard.edu's Karen Cichowski spoke at #AACR2026 about her work as a member of a Cancer Grand Challenges team exploring how epigenetic changes cooperate with oncogenes to drive tumor and tissue specific biology, and the therapeutic vulnerabilities such idiosyncrasies expose.
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Ludwig Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research
One of the biggest challenges in cancer research is effective cancer prevention. The ATLAS team is exploring how the body’s natural defences may help prevent cancer from developing in the first place. By studying people who avoid cancer despite age, genetics or lifestyle risk factors, researchers hope to uncover what makes these ‘cancer avoiders’ different. The team believes antibodies could hold an important part of the answer. Learn more about ATLAS and follow the team’s progress ➡️ https://www.cancergrandchallenges.org/atlas ATLAS is funded by @CancerResearchUK and the Torrey Coast Foundation through Cancer Grand Challenges. Team Leadership: Paul Bastard – Institute IMAGINE, France Co-Investigators: Jean-Laurent Casanova – UT Southwestern Medical Center, US. Jacques Fellay – EPFL & Lausanne University Hospital, Switzerland. Tyler Hulett – CDI Laboratories, US. Trine Hyrup Mogensen – Aarhus University, Denmark. Nils Landegren – Uppsala University, Sweden. Xin Lu – Ludwig Institute for Cancer Research, University of Oxford, UK. Ruth Travis – Oxford Population Health, University of Oxford, UK. Chi Van Dang – Ludwig Cancer Research, US. Patient Advocates: Sue Friedman – US. Karl Smith-Byrne – UK. Cancer Grand Challenges is a global research initiative, co-founded by Cancer Research UK and the National Cancer Institute in the US, that brings together world-class interdisciplinary teams to tackle some of cancer’s toughest challenges, with more than £465 million invested to date. Subscribe: https://www.youtube.com/@CancerGrandChallenges LinkedIn: https://www.linkedin.com/company/cancergrandchallenges/ X: https://x.com/home Bluesky: https://bsky.app/profile/cancergrand.bsky.social Website: https://www.cancergrandchallenges.org/
