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I am delighted to share new work with Simon Myers (www.biorxiv.org/content/10.6...), on how genetic variants that influence binding patterns of PRDM9 and slow down the repair of meiotic double-strand breaks impact mammalian spermatogenesis and fertility. 1/n
1/n Check out our new paper, spearheaded by @fborne.bsky.social, just out in PLoS Genetics doi.org/10.1371/jour....
doi.org
www.biorxiv.org
Author summary Proteins fold into three-dimensional structures that are essential for their function. Because these structures depend on interactions among amino acids, the fitness effect of a mutatio...
Epistasis among clustered lineage-specific amino acid substitutions in the Drosophila Trio protein
10h
27d
Thrilled to present my dissertation research at the Hamilton Symposium! We used approaches including GWAS, long-read sequencing, phylogenetic methods, and behavior experiments to uncover the genetic basis and evolutionary history of a shared polymorphism. Can’t wait to share what we’ve learned!
Ipsita Agarwal
Peter Andolfatto
28d
Tris Dodge
Excited to share this new pre-print from the fantastic @kelsiehunnicutt.bsky.social! Kelsie put together a thoughtful and thorough review on hybridization in animal evolution: ecoevorxiv.org/repository/v.... She tracks notable shifts in perspectives on the study of hybridization through time.