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We also improved our interactive website to explore this data and results so take a look for yourself: jef.works/CellCarto-Co... Congrats to Sami Singh, Dee Velazquez, with Hamid Rabb + team 🎉
1mo
We've updated our preprint characterizing the spatiotemporal impact of cold ischemia in mouse kidney to better understand the molecular underpinnings of cold-storage injury in kidney transplants. Check it out: www.biorxiv.org/content/10.1... 🧵👇
In this blog post, I demo how I went from a question ➡️ "how have gas prices changed in different regions across the US over time?" ➡️ to using AI to find relevant data ➡️ to using AI to vibe code this data visualization to answer my question: jef.works/blog/2026/05... Try it out for yourself!
Before cameras, only painters could "capture reality." After, people said cameras would replace painters. But painting evolved. Now, people say AI will replace programmers. So, I reflect on things painting in the age of cameras can teach us about coding in the age of AI: jean.fan/2026/04/22/a...
Increased durations of cold ischemia is implicated in poor transplant outcomes, but the molecular mechanisms remain unclear. Using spatial transcriptomics, we profiling cold ischemia injury using a mouse model to identify temporally-resolved gene expression changes in a compartment-specific manner.
Our spatiotemporal transcriptomic analysis thus identified coordinated molecular changes within metabolic pathways deep within the cold ischemic kidney, highlighting potential opportunities for new insights beyond those available from superficial biopsy-focused tissue examinations.