A Crossed Laser Phase Plate for CryoEM https://www.biorxiv.org/content/10.64898/2026.06.05.730245v1
Love these little guys - seen while walking in the park
The results here re 3D classification are quite impressive. Would be interesting to see how much the LPP improves classification of near-native samples with extreme compositional heterogeneity (e.g. derived from cellular fractions)
Very sad to learn that Steve White has passed away.