Thank you to Bob McDonald for hosting me on @CBCRadioCanada to discuss our work @yaleschoolofmed.bsky.social on what leads to variation in common cold virus infections and how we tackled this using nasal organoids. Listen here: www.cbc.ca/listen/live-...
Excited to see this beautiful image of nasal #organoids featured as biomedical Image of the day by @cellpress.bsky.social 🙏🙏🙏 See full paper @cellpressblue.bsky.social #respiratory #lungs #EpithelialMechanics #IdSky #MedSky #ImmunoSky
#Epithelialmechanics fans...interferons protect against viruses but also impair recovery post-infection. In new work @plosbiology.org we show that interferons block epithelial repair by co-opting the Hippo pathway #innateimmunity #lungs #respiratory journals.plos.org/plosbiology/...
#Interferons protect against #ViralInfection, but can hinder tissue repair - how? @ellenfoxman.bsky.social &co show that high IFN levels suppress #BronchialCell migration & proliferation during tissue repair via JAK-driven LATS1 activation, independent of STAT1 @plosbiology.org 🧪 plos.io/4k1pyKA
#Interferons protect against #ViralInfection, but can hinder tissue repair - how? @ellenfoxman.bsky.social &co show that high IFN levels suppress #BronchialCell migration & proliferation during tissue repair via JAK-driven LATS1 activation, independent of STAT1 @plosbiology.org 🧪 plos.io/4k1pyKA
#InterferonFriendsOrFoes? Another cool one @ellenfoxman.bsky.social &friends out @plosbiology.org about how excessive #IFNs delay repair by activating LATS & degrading YAP/TAZ in the Hippo 🦛 pathway! journals.plos.org/plosbiology/... 👇👇👇
Mechanistic insights into the impact of prenatal viral infections on maternal and offspring immunity
www.nature.com/articles/s44...
Frequent presymptomatic household transmission of influenza A but not influenza B virus
www.nature.com/articles/s44...
Rhinovirus triggers distinct host responses through differential engagement of epithelial innate immune signaling @ellenfoxman.bsky.social @yalepress.bsky.social
www.cell.com/cell-press-b... @cellpressblue.bsky.social
