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ICREA Research Professor. Evolution, Genetics, Neuroscience, Linguistic Cognition https://www.cedricboeckx.com

1/11 Happy to share our TICS paper on using the flexibility of one of the most basic cognitive functions, perception, to understand one of the most complex cognitive dysfunctions, psychiatric conditions (also my first formal work in computational psychiatry 🎉) 📄: www.cell.com/trends/cogni... 🧵 : 👇

Fascinating new work linking schizophrenia to cilia By @hyejungwon.bsky.social @martinowk.bsky.social @stephaniehicks.bsky.social @kr-maynard.bsky.social “first in-vivo characterization of the consequence of common variant architecture in SCZ; ciliary dysfunction as a convergent mechanism” 🧪🧬🧠

Online Now: Perceptual multistability: a multifaceted window into brain dysfunctions

Congrats to Jiseok Lee and others in @hyejungwon.bsky.social lab on this set of exciting findings that begin to explain how common variants in schizophrenia mediate functional effects. Honored for our teams to have played a role and to see our new SCZ data get integrated into a study so quickly!!

Cool new paper by Yujie Zhao et al. www.nature.com/articles/s41... (Tagging who I know on bsky @bennystrobes.bsky.social @mikeinouye.bsky.social) This paper touches on the topic of pleiotropy in gwas, i.e. are the same genetic variants (SNPs) seemingly important for multiple phenotypes?

Congrats to all the awardees 👏👏

A very good read: “Recent progress in studies of the last million years of human physical and behavioural evolution” Review by @jamescolearch.bsky.social @elliescerri.bsky.social @matejahajdi.bsky.social @chrisbstringer.bsky.social 🧪💀 rai.onlinelibrary.wiley.com/doi/10.1111/...

Very cool new work on cortical folding, led by @r3rt0.bsky.social, showing the influence of the geometry of the the unfolded neocortex 🧪🧠 www.biorxiv.org/content/10.6...

Outstanding new study tracking the changes in Purkinje neuron dendritic architecture during primate evolution, documenting an increase in dendritic compartmentalization in the human lineage Study by @auroraferrell.bsky.social @neurosilas.bsky.social & colleagues 🧪🧠 #cerebellum

Schizophrenia (SCZ) is a common psychiatric disorder characterized by psychosis, emotional withdrawal, and cognitive deficits. Most SCZ risk variants reside in non-coding regions of the genome and are...

Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics and information integration during percept formation often distinguish clinical from nonclinical populations. Computational psychiatry can elucidate these variations through two primary approaches: (i) Bayesian modeling, which treats perception as an unconscious inference, and (ii) an active, information-seeking perspective (e.g., reinforcement learning), which frames perceptual switches as internal actions. Our synthesis aims to leverage multistability to bridge these computational psychiatry subfields, linking human and animal studies as well as connecting behavior to underlying neural mechanisms. Perceptual multistability emerges as a promising noninvasive tool for clinical applications, facilitating translational research and enhancing our mechanistic understanding of cognitive processes and their impairments.

Pleiotropic shared heritability with bias correction (PHBC) estimates the genetic variance of a target disease that is shared with a set of auxiliary diseases. Applying PHBC to diseases in the UK Biob...

Trends in Cognitive Sciences

This article presents a synthesis of recent developments in the study of human evolution over the past five years. It begins with an overview of hominin species nomenclature and diversity, followed b...

rai.onlinelibrary.wiley.com

Cortical folding patterns are conserved across individuals of gyrencephalic species and are closely related to cytoarchitectural organisation, connectivity, and function. Early morphogen gradients hav...

Vertebrate evolution has driven adaptive remodeling of brain regions impacted by changing sensorimotor demands. The cerebellum--a hindbrain area mediating associative learning and predictive coding--i...

We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/

Leading Edge Fellows Program