Cool new paper by Yujie Zhao et al. www.nature.com/articles/s41...
(Tagging who I know on bsky @bennystrobes.bsky.social @mikeinouye.bsky.social)
This paper touches on the topic of pleiotropy in gwas, i.e. are the same genetic variants (SNPs) seemingly important for multiple phenotypes?
Pleiotropic shared heritability with bias correction (PHBC) estimates the genetic variance of a target disease that is shared with a set of auxiliary diseases. Applying PHBC to diseases in the UK Biob...