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One week left to apply for the postdoc position in my lab at Oxford @ox.ac.uk Join our exciting cancer immunology research at @oncology.ox.ac.uk, @oxfordcancer.bsky.social & @oxcio.bsky.social. Deadline: 11 August 2025 (noon).
We're recruiting a postdoc to join my lab at @oncology.ox.ac.uk & @oxcio.bsky.social to understand immune regulation in cancer and develop new approaches for cancer prevention and metastasis. Deadline: 11 August 2025 my.corehr.com/pls/uoxrecru... Lab info: www.oncology.ox.ac.uk/team/jie-yang
10mo
11mo
Research Highlight of our recent paper by @jieyang437.bsky.social on Aspirin and cancer metastasis in Nature Reviews Immunology. Thanks to Yvonne Bordon for a crystal clear account of the experimental findings www.nature.com/articles/s41...
New results from the ALASCCA prospective randomised controlled trial showing daily #aspirin reduces colorectal cancer recurrence by ~50% in patients with PIK3CA or related mutations. Findings extend benefits of aspirin beyond Lynch syndrome cancers to nearly 40% of CRCs ascopubs.org/doi/10.1200/...
Brilliant new paper from Jie Yang @jieyang437.bsky.social and Rahul Roychoudhuri @roychoudhurilab.bsky.social linking aspirin to immune-mediated prevention of cancer metastasis. www.nature.com/articles/s41...
Congrats to @jieyang437.bsky.social & Rahul for this awesome work on metastasis www.nature.com/articles/s41...
Mar 25, 2025
my.corehr.com
Job Details
Mar 25, 2025
Mar 5, 2025
Mar 6, 2025
Jie Yang
Jie Yang
Seth Coffelt
Klaus Okkenhaug
Roychoudhuri Lab
Roychoudhuri Lab
Drugs like aspirin can enhance the anti-metastatic activity of T cells by blocking a platelet-mediated pathway of suppression.
www.nature.com
Aspirin helps T cells to stop cancer spread - Nature Reviews Immunology
www.nature.com
Inhibition of cyclooxygenase 1 releases T cells from immunosuppression by platelet-derived thromboxane A2, thereby enhancing the immune response against metastasis.
Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity - Nature
LBA125Background: Colorectal cancer (CRC) affects 1.9 million individuals globally each year. Among patients with stage II-III CRC, 20-40% develop metastatic disease. Aspirin lowers the incidence of a...
ascopubs.org
Low-dose aspirin to reduce recurrence rate in colorectal cancer patients with PI3K pathway alterations: 3-year results from a randomized placebo-controlled trial.
We're recruiting a postdoc to join my lab at @oncology.ox.ac.uk & @oxcio.bsky.social to understand immune regulation in cancer and develop new approaches for cancer prevention and metastasis. Deadline: 11 August 2025 my.corehr.com/pls/uoxrecru... Lab info: www.oncology.ox.ac.uk/team/jie-yang
11mo
Job Details
my.corehr.com
Jie Yang
www.nature.com
Inhibition of cyclooxygenase 1 releases T cells from immunosuppression by platelet-derived thromboxane A2, thereby enhancing the immune response against metastasis.
Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity - Nature