I was today years old when I realized that the Chromosome 2 fusion event which is unique to modern humans probably coincides with a possible population bottleneck event ~900kya.
Could the one have caused the other?
This is my adaptation of the published figure
DOI: 10.1126/science.abq7487
Hello, world!
The most famous heuristic in mapping gwas snps to genes is "it's usually the closest gene".
But only slightly less well-known is this: consider the colocalized phenotypes.
That is, a genetic variant seldom disrupts exactly one phenotype.
What else does tugging on that thread do?
Here we are, looking forward to 2 days of exciting Genomics! If you're at the event and in need of a Bioinformatician, I'm open for new positions! 😁
RapidoPGS 2.3.1 is now available on CRAN 🥳 (cran.r-project.org/web/packages...).
Changes in dependencies were making RapidoPGS multi to fail. This new version should work as expected. Test it out!