Researching the interplay between factors underlying metabolic health and disease, including diet, age, environment, and genetics, for the prevention and treatment of widespread chronic diseases. https://hsph.harvard.edu/department/molecular-metabolism/
Harvard Molecular Metabolism
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Photo Credit: Kent Dayton @hsph.harvard.edu
Last week we celebrated two Tashjian Award recipients for Junior Faculty: Dr. Jessalyn Ubellacker and Dr. Young Yon. Their innovative work on cancer metabolism, ferroptosis, and cancer cachexia advances how we understand and treat disease. Honored to recognize their achievements and future impact.
New study in iScience - @met-hsph.bsky.social researchers in @tonyhui.bsky.social lab show that key phenotypes of cancer cachexia can be simply due to reduced food intake, demonstrating the critical importance to separate food intake-dependent and -independent effects while studying cancer cachexia.
Thrilled to share that our colleague Jessalyn Ubellacker, MD, PhD @ubellackerlab.bsky.social has been selected as a recipient of an AACR Trailblazer Cancer Research Grant—a prestigious $1M award supporting bold, innovative cancer research. Huge congratulations, Jessalyn!
In Wiley Advanced Science @mariesabatier.bsky.social, @ubellackerlab.bsky.social, and colleagues examine GPX4 inhibitor resistance in triple-negative breast cancer, showing that resistant cells survive in circulation but lose the ability to spontaneously metastasize from primary tumors. hsph.me/GPX4
Mapping the “exposome” to protect health.
@penggao.bsky.social, uses high-resolution mass spectrometry and multi-omics to reveal how pollutant mixtures shape asthma, cancer, Alzheimer’s risk, and more.
Read about the work. in the Gao Lab: hsph.me/hpiitbtih31026
#Exposomics #EnvHealth
“How do we not just live longer, but live better?”
A great profile from January of Maria Perez-Matos, PhD ’25, from the Mair Lab (@willmair.bsky.social), on uncovering molecular clues to healthy aging and longevity—down to tiny worms and oleic acid.
Read more: hsph.me/llb13026
Honored to share that Dr. Gökhan Hotamışlıgil has been elected to the National Academy of Sciences, one of the highest distinctions in science recognizing outstanding, sustained contributions to research.
Huge congratulations to Dr. Hotamışlıgil on this remarkable and well-deserved honor!
Clear evidence from Josh Shin in our lab that mTORC1 signaling and autophagy reciprocally influence the length of primary cilia. Question remains how do changes in length affect cilia signaling and function in the largely quiescent cells comprising our brains and bodies. www.cell.com/iscience/ful...
Harvard Molecular Metabolism
WASHINGTON — The National Academy of Sciences announced today the election of 120 members and 25 international members in recognition of their distinguished and continuing achievements in original res...
