Phage-host interactions have a role shaping microbial ecosystems, but what happens in #microgravity? Experiments aboard the #ISS reveal distinct evolutionary adaptations in T7 bacteriophage & #Ecoli, revealing #phage variants effective against resistant pathogens @plosbiology.org 🧪 plos.io/3LtKOfs
PLOS Biology
"That telomere phages are so prevalent means that they are a selective force, one that we know little about. We now want to understand how the telomere-toxin is secreted and also understand how this ‘telocin’ wheedles its way into unsuspecting bacterial neighbors”
www.science.org/doi/10.1126/...
hey, that's me!
Trevor Lithgow
Did you know that there is so much DNA packed inside a phage capsid that the pressure is 10X higher than in a bottle of champagne? In our latest preprint, we wondered how that is contained in a phage that lives at extremely high temperatures. /1
www.biorxiv.org/content/10.1...
Emma Sedivy
Brian Kelch
www.biorxiv.org/content/10.1...
NEW PREPRINT ALERT!
Thanks to all involved!
Grigorieff Lab @UMassChan and @HHMI
Klebsiella host strains infected with telomere phages can grow to be the dominant lineage in mixed populations.
The structure of a thermostable phage's Portal Vertex and Neck Complex illuminates its maturation process www.biorxiv.org/content/10.1101/2025.04.14.648768v1 #cryoEM
