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Now out in Science Advances: www.science.org/doi/10.1126/...
Decoding influenza virus: From polymerase mechanisms to translational therapeutics www.sciencedirect.com/science/arti...
RNA structure modulates Cas13 activity and enables mismatch detection - @cambearon.bsky.social @princetonmolbio.bsky.social go.nature.com/4oglebG
Excited to share our latest preprint in which we integrate mathematical modeling with experimental approaches to investigate how ⬆️ temperature influences aberrant RNA synthesis and innate immunity in flu infection 🦠
3-year-old girl dies from H5N1 bird flu in Mexico’s first human case bnonews.com/index.php/20...
5mo
4mo
Flu infection => temperature⬆️ => NP levels⬇️ => aberrant RNAs⬆️ => interferon⬆️. Elegant modeling and experimental work by @karishmabisht.bsky.social and @danielweilandt.bsky.social! Preprint: www.biorxiv.org/content/10.1...
Transient RNA structures play a key role in the emergence of highly pathogenic avian influenza viruses! Great to see this collaboration with Mathis Funk, Mathilde Richard, Stephen Cusack, and others in @science.org www.science.org/doi/10.1126/...
7mo
May 20, 2025
Congratulations to @karishmabisht.bsky.social with her paper on the effect of fever on influenza replication and innate immune activation! www.science.org/doi/10.1126/...
There is still time to apply; join our team to work on influenza virus replication mechanisms!
Apr 8, 2025
May 20, 2025
3mo
5mo
May 26, 2025
AJ te Velthuis
Highly pathogenic avian influenza viruses (HPAIVs) derive from H5 and H7 low pathogenic avian influenza viruses (LPAIVs). Although insertion of a furin-cleavable multibasic cleavage site (MBCS) in the...
www.science.org
Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis
Nature Biotechnology
Fever promotes aberrant influenza A virus RNA synthesis and innate immune activation.
www.science.org
Febrile temperature activates the innate immune response by promoting aberrant influenza A virus RNA synthesis
Ervin Fodor
Karishma Bisht
BNO News
AJ te Velthuis
AJ te Velthuis
Fever promotes aberrant influenza A virus RNA synthesis and innate immune activation.
www.science.org
Febrile temperature activates the innate immune response by promoting aberrant influenza A virus RNA synthesis
AJ te Velthuis
Ervin Fodor
A three-year-old girl who became Mexico’s first confirmed human case of H5N1 avian influenza has died, the country’s Health Ministry announced. It marks Mexico’s first fatality linked to the bird flu ...
bnonews.com
3-year-old girl dies from H5N1 bird flu in Mexico’s first human case
www.biorxiv.org
An effective CRISPR RNA occlusion strategy enhances mismatch detection when using Cas13.
go.nature.com
RNA structure modulates Cas13 activity and enables mismatch detection - Nature Biotechnology
Flu infection => temperature⬆️ => NP levels⬇️ => aberrant RNAs⬆️ => interferon⬆️. Elegant modeling and experimental work by @karishmabisht.bsky.social and @danielweilandt.bsky.social! Preprint: www.biorxiv.org/content/10.1...
Exciting job opportunities! Two postdoc positions are available in the Fodor Lab at @dunnschool.bsky.social to study influenza virus transcription, genome replication, nuclear export and assembly. More info: my.corehr.com/pls/uoxrecru...
May 20, 2025
May 7, 2025
www.biorxiv.org
AJ te Velthuis
Ervin Fodor