See extensive thread by @sjoerdmeijer.bsky.social β‘οΈ
bsky.app/profile/sjoe...
Studies seem to show that research is becoming less βdisruptiveβ of established ideas.
And this is a problem.
@nature.com
π§ Congrats @felixklaassen.bsky.social with this unique DBS case study targeting the midbrain PAG. Direct PAG stimulation (and not a bordering control region) induces threat-specific bradycardia β€οΈ @devoogdld.bsky.social @anneloeshulsman.bsky.social & co-authors www.tandfonline.com/doi/full/10....
π§ Can brain stimulation help socially anxious people approach what they fear? π π°
We used synchronized electrical brain stimulation to improve control over emotional behaviour in social anxiety, while scanning their brains to understand who responds best and why.
ππ doi.org/10.1523/JNEU...
The end of academic freedomβ¦
www.science.org/content/arti...
This case review remains important highlight to avoid misunderstandings
Very interesting work! Congrat Johannes, fantastic to see all this amygdala-TUS work coming out now.
The ability to recognize and anticipate potential danger is crucial for survival across species. The midbrain periaqueductal gray (PAG) is implicated in regulating threat-anticipatory responses, in...
A new way to improve emotion control in social anxiety by targeting rhythmic brain circuits via dual-site tACS: www.jneurosci.org/content/earl...
PhD Position: Computational Affective Neuroscience and Ultrasonic Neuromodulation at @dondersinst.bsky.social
>Passionate about ultrasonic modulation? Come and join us! funded by @erc.europa.eu HEART2ADAPT @epanlab.bsky.social in coll. with @lennartverhagen.bsky.social
www.ru.nl/en/working-a...
Super proud of @sjoerdmeijer.bsky.social who demonstrated that amygdala-TUS slows initial threat acquisition and enhances subsequent extinction. Great collaboration with @lennartverhagen.bsky.social and @deVoogdld.bsky.social ea. Thanks to @ERC.europa.eu.
www.science.org/doi/10.1126/...
Karin Roelofs
Karin Roelofs
Liuba Papeo
Sjoerd Meijer
Sweeping proposed rule, now open for comments, would also restrict foreign collaborations and remove federal funding for open-access fees
π§ What makes threat memories so hard to forget? ππ±
Using focused ultrasound we provide causal evidence that the human amygdala drives rapid threat learning πβ‘ and determines how resistant those memories become to subsequent extinction ππ«
ππ www.science.org/doi/10.1126/...
Social avoidance is a hallmark of social anxiety disorder. Difficulties in controlling avoidance behavior are the core maintaining factor of this impairing condition, hampering the efficacy of existin...
www.jneurosci.org
Do you want to work as a PhD 'Computational Affective Neuroscience and Neuromodulation' at the Faculty of Social Sciences? Check our vacancy!
A brain injury was reported in a trial using ultrasound, framed as low-intensity TUS. Kim Butts Pauly and I reviewed the case and disagreed with how it's presented. Key acoustic data are missing.
Case: doi.org/10.1016/j.br...
Letters: www.elsa-fouragnan.com/blog | web.stanford.edu/~kimbutts/Le...
Ultrasonic neuromodulation of the human amygdala provides causal evidence for its role in forming persistent threat memories.
Very happy our first paper using ultrasound stimulation (TUS) to stimulate the human amygdala (BLA) got out in @cp-neuron.bsky.social today! ππ₯³πGreat FUN with co-first authors @mirunmigyu.bsky.social @lilweb.bsky.social in @mkflugge.bsky.social 's lab!
www.sciencedirect.com/science/arti...
www.sciencedirect.com
The amygdala shows abnormal metabolism in depression, a disorder marked by altered emotion, motivation, and learning. Yet its causal role in these proβ¦