Experimental Psychopathology and Affective Neuroscience (Donders Institute and Behavioral Science Institute, Radboud University)
https://www.epanlab.nl/
Karin Roelofs
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A new way to improve emotion control in social anxiety by targeting rhythmic brain circuits via dual-site tACS: www.jneurosci.org/content/earl...
Very interesting work! Congrat Johannes, fantastic to see all this amygdala-TUS work coming out now.
This case review remains important highlight to avoid misunderstandings
See extensive thread by @sjoerdmeijer.bsky.social ➡️
bsky.app/profile/sjoe...
PhD Position: Computational Affective Neuroscience and Ultrasonic Neuromodulation at @dondersinst.bsky.social
>Passionate about ultrasonic modulation? Come and join us! funded by @erc.europa.eu HEART2ADAPT @epanlab.bsky.social in coll. with @lennartverhagen.bsky.social
www.ru.nl/en/working-a...
🧠 Congrats @felixklaassen.bsky.social with this unique DBS case study targeting the midbrain PAG. Direct PAG stimulation (and not a bordering control region) induces threat-specific bradycardia ❤️ @devoogdld.bsky.social @anneloeshulsman.bsky.social & co-authors www.tandfonline.com/doi/full/10....
Karin Roelofs
Super proud of @sjoerdmeijer.bsky.social who demonstrated that amygdala-TUS slows initial threat acquisition and enhances subsequent extinction. Great collaboration with @lennartverhagen.bsky.social and @deVoogdld.bsky.social ea. Thanks to @ERC.europa.eu.
www.science.org/doi/10.1126/...
Karin Roelofs
The end of academic freedom…
www.science.org/content/arti...
Karin Roelofs
Studies seem to show that research is becoming less ‘disruptive’ of established ideas.
And this is a problem.
@nature.com
🧠 Can brain stimulation help socially anxious people approach what they fear? 😠😰
We used synchronized electrical brain stimulation to improve control over emotional behaviour in social anxiety, while scanning their brains to understand who responds best and why.
🆕📄 doi.org/10.1523/JNEU...
Do you want to work as a PhD 'Computational Affective Neuroscience and Neuromodulation' at the Faculty of Social Sciences? Check our vacancy!
Social avoidance is a hallmark of social anxiety disorder. Difficulties in controlling avoidance behavior are the core maintaining factor of this impairing condition, hampering the efficacy of existin...
The ability to recognize and anticipate potential danger is crucial for survival across species. The midbrain periaqueductal gray (PAG) is implicated in regulating threat-anticipatory responses, in...
Very happy our first paper using ultrasound stimulation (TUS) to stimulate the human amygdala (BLA) got out in @cp-neuron.bsky.social today! 🎉🥳🔊Great FUN with co-first authors @mirunmigyu.bsky.social @lilweb.bsky.social in @mkflugge.bsky.social 's lab!
www.sciencedirect.com/science/arti...
🧠 What makes threat memories so hard to forget? 🐍😱
Using focused ultrasound we provide causal evidence that the human amygdala drives rapid threat learning 🐍⚡ and determines how resistant those memories become to subsequent extinction 🐍🚫
🆕📄 www.science.org/doi/10.1126/...
The amygdala shows abnormal metabolism in depression, a disorder marked by altered emotion, motivation, and learning. Yet its causal role in these pro…
Ultrasonic neuromodulation of the human amygdala provides causal evidence for its role in forming persistent threat memories.
www.science.org
Johannes Algermissen
A brain injury was reported in a trial using ultrasound, framed as low-intensity TUS. Kim Butts Pauly and I reviewed the case and disagreed with how it's presented. Key acoustic data are missing.
Case: doi.org/10.1016/j.br...
Letters: www.elsa-fouragnan.com/blog | web.stanford.edu/~kimbutts/Le...
