The team went to the #biophysical and #modeling side to understand how the CaBP1 protein regulates L-type channels. Great collab with Jim Ames, Hell Lab & #MnMLab
@ucdavis.bsky.social
pubs.acs.org/doi/10.1021/...
pubs.acs.org
The L-type voltage-gated Ca2+ channel (CaV1.2) controls gene expression, cardiac function, and neuronal excitability. Mutations in CaV1.2 that disrupt channel function are implicated in cardiac arrhyt...