Long wondered if the rules being elucidated in the nucleous apply more broadly to transcriptional condensates? Talked about this with @superscijew.bsky.social over the years. Thoughts? Congrats on paper.
See our handy graphical abstract and article for free here:
bit.ly/4vsl845
Jon Henninger
Check out our new work in Cell Systems @cp-cellsystems.bsky.social! Much of the biochemistry in the cell is organized by biomolecular condensates, but what mechanisms control the distribution of a given condensate throughout the cell? And is this mesoscale organization important for function?
Bede Portz
Jon Henninger
How are biomolecular condensates spatially organized? As example, we focus on fibrillar centers producing ribosomal RNA in the nucleolus. Disrupting this function disrupts their patterning, and disrupting patterning disrupts function. Out in Cell Systems: authors.elsevier.com/c/1nA3C8YyDf... (1/6)
