“With a liberal non-inferiority margin, amitriptyline is non-inferior…in reducing insomnia severity. Amitriptyline has more side effects & its effect on insomnia may diminish after tapering. [CBT-I]should remain first-line treatment for patients with medical comorbidity given its broader benefits.”
Nicole Tang
#CognitiveBehavioralTherapy (CBT-I) remains the most popular #insomniatreatment. In this clinical trial, researchers explore #amitriptyline as a potential #insomniatreatment for patients with #medicalcomorbidities.
academic.oup.com/sleep/articl...
AbstractStudy objectives. In a randomized controlled non-inferiority trial, we aimed to determine whether low-dose amitriptyline, which is often used off-l
