Reviewing the paper by the Kats´ lab published today in #Cell, "Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia", I learned that cuproptosis is real! Here is my preview:
When heme is low, copper kills cancer:
www.cell.com/cell/fulltex...
Heme carries oxygen and is critical for the control of redox reactions. In this issue
of Cell, Lewis and Gruber et al. demonstrate how low concentrations of heme destabilize
complex IV of the respirat...
