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Archaea-on-bacteria action! @romainstrock.bsky.social @tobiaswarnecke.bsky.social &co show that many #archaea encode #peptidoglycan hydrolases, which specifically target #bacterial cell walls, experimentally confirming the killing capacity of 2 of these enzymes @plosbiology.org 🧪 plos.io/4lrJBBa
10mo
The MIMIC lab is hiring a Postdoctoral Research Associate to join my team at @Cambridge_Uni! Exploration and engineering DNA-mimicking proteins (wet-lab position.) 🧬 Details: www.jobs.cam.ac.uk/job/50652/ Please get in touch / circulate !
Mar 22, 2025
Why did severe #StrepA infections in children increase after the pandemic? Our new @jamanetworkopen paper suggests COVID restrictions delayed immunity development in young children. tiny.cc/63vt001
8mo
Applications for @ukri.org Medical Research Council funded MRes+PhD studentships in Interdisciplinary Health Sciences at @imperialcollege will open on Tuesday 7 October. www.imperial.ac.uk/multisci-mrc... #PhD #Interdisciplinaryhealthscience #Scholarships
This first-author publication is my… first! Archaea kill bacteria by targeting their Achilles’ heel: peptidoglycan. Big shoutout to @ahocher.bsky.social‬, @valeriesoo.bsky.social‬, Pauline Misson, @tobiaswarnecke.bsky.social‬ and MRC LMS Proteomics. A thread 🔽 journals.plos.org/plosbiology/...
PLOS Biology
10mo
8mo
Researchers CBRB welcomed colleagues from WACCBIP as part of an Imperial Global Connect visit. The event aimed to strengthen international partnerships and advance discovery research in bacterial antimicrobial resistance (AMR). 🔬 www.imperial.ac.uk/news/article...
7d
Imperial MRC DTP
The 2024 rankings of bacterial threats
Putting our deductive, problem-solving, and team-working skills to good use - we had so much fun at the Sherlock Escape Room aaand we escaped in 53 minutes! #teampbp #escaperoom
11mo
9mo
Department of Infectious Disease
We are only beginning to understand the breadth of enzyme diversity in the archaeal world. Here's an example of how an archaeon can deploy a phospholipase to kill certain bacteria... www.biorxiv.org/content/10.6...
Very happy to see this work published + getting the recognition it deserves! Archaea are very cool + understudied organisms and we are only scratching the surface! Since the preprint last year, we (@romainstrock.bsky.social) have included more evidence of bacteria getting killed by archaeal arsenal.
10mo
Romain Strock
5d
Archaea kill bacteria, at least on occasion. The molecular underpinnings of these lethal interactions are barely understood. Here, we describe cinquedea, an α/β hydrolase secreted by the halophilic ar...
www.biorxiv.org
A Bactericidal Phospholipase from Archaea
www.jobs.cam.ac.uk
Research Associate (Fixed Term) in the Department of Genetics at the University of Cambridge.
Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Vaughn Cooper
Valerie Soo
Valerie Soo
Valerie Soo
Archaea are the hornets of the microbial world. Discuss. www.biorxiv.org/content/10.6... TLDR: Archaeon kills bacterium with secreted phospholipase. Pretty nifty way to kill bacteria for a microbe with a very different lipid make-up, I reckon. No need to worry about accidentally killing yourself.
5d
www.biorxiv.org
Tobias Warnecke
Applications for 2026 entry will open on Tuesday 7 October 2025 at midday (BST) and close at 23:59 (GMT), Tuesday 18 November 2025.
www.imperial.ac.uk
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Archaea regularly interact with bacteria but reports of archaea killing bacteria are very rare. This study shows that many archaea encode peptidoglycan hydrolases, which specifically target bacterial ...
journals.plos.org
Archaea produce peptidoglycan hydrolases that kill bacteria
This cross-sectional study examines changes in immunity to Streptococcus pyogenes and other common respiratory pathogens among young children in 10 European countries after the introduction of nonphar...
tiny.cc
Immunity to S pyogenes and Common Respiratory Viruses at Age 0 to 4 Years
Antoine Hocher
Awesome to see the transparent, systematic, and evidence-based approach behind the WHO Bacterial Priority Pathogens List 2024 out in the Lancet Infectious Diseases www.thelancet.com/journals/lan...
9mo
Kate Baker
Archaea are often surrounded by bacteria. But is there ever active conflict between the two? Can archaea kill bacteria? If so, how do they do it? Work by @romainstrock.bsky.social shows that some archaea can kill bacteria by secreting peptidoglycan hydrolases. journals.plos.org/plosbiology/...
10mo
Archaea produce peptidoglycan hydrolases that kill bacteria
journals.plos.org
Archaea regularly interact with bacteria but reports of archaea killing bacteria are very rare. This study shows that many archaea encode peptidoglycan hydrolases, which specifically target bacterial ...
Tobias Warnecke
www.thelancet.com
The 2024 WHO BPPL is a key tool for prioritising research and development investments and informing global public health policies to combat AMR. Gram-negative bacteria and rifampicin-resistant M tuber...
The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance