How do you kill a MRSA superbug armed with 15 different anti-phage defense systems? You make a smarter phage. Check out our latest preprint on overcoming bacterial immunity using defense-guided engineering to build durable therapeutic phage cocktails! Led by Sarah Voss. doi.org/10.64898/202...
#SISB2026 was fantastic! A big thanks to the organisers - super inspiring event!
That's a wrap on three days of incredible science at #SISB2026! Special thanks to @rockefeller.edu for hosting us on their beautiful campus, to our speakers and poster presenters, and most of all to this community that never fails to inspire. Can't wait for #SISB2027 🫶
The 2026 symposium on the immune system of bacteria, New York, May 5-7
A fantastic lineup of speakers, looking forward to seeing top unpublished discoveries on bacterial immunity
We'll be there with many lab members, sharing new stories, we'll be very happy to get feedback on :)
Really looking forward.
Out today: We discovered new viral proteins that target immune signaling molecules, solely based on their AlphaFold-predicted shapes
www.science.org/doi/10.1126/...
Congrats Nitzan Tal and coauthors! Thank you Kranzusch lab for the fun collaboration!
Linking below previous thread on our findings
Last day to submit your abstracts!
sisb2026.rockefeller.edu
Modell lab
With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...
That's a wrap on three days of incredible science at #SISB2026! Special thanks to @rockefeller.edu for hosting us on their beautiful campus, to our speakers and poster presenters, and most of all to this community that never fails to inspire. Can't wait for #SISB2027 🫶
Our lab is hiring!
As our fierce technician is moving on to graduate school (GO ANNA!), we’re looking for a new tech to join our team studying bacteria-phage interactions.
Ideal for recent grads interested in molecular biology and microbiology - please reach out with a CV to [email protected].
Daan C. Swarts
Very cool perspective on cellular resources and co-dependence!
Naama Aviram
Immune systems in animals, plants, and bacteria often rely on intracellular nucleotide signaling, which viruses can block by sequestering or degrading these signals. We identified structural and bioph...
Abstract submission is now OPEN for the 2026 Symposium on the Immune System of Bacteria!
sisb2026.rockefeller.edu
🗓 May 5–7, 2026
📍 Rockefeller University, New York City
⏰ Abstract deadline: March 16, 2026
Attendance will be capped, be sure to register early and secure your spot.
See you in NYC!
Abstract submission is now OPEN for the 2026 Symposium on the Immune System of Bacteria!
sisb2026.rockefeller.edu
🗓 May 5–7, 2026
📍 Rockefeller University, New York City
⏰ Abstract deadline: March 16, 2026
Attendance will be capped, be sure to register early and secure your spot.
See you in NYC!
📢Preprint out!
Excited to share my final work from the @soreklab.bsky.social!
We mined phage dark matter using structural features shared by anti-defense proteins (viral tools that help phages bypass bacterial immunity) to guide discovery.
Found 3 new families targeting immune signaling!
Our lab is excited to share unpublished research on phage defense at the upcoming 2026 Symposium on the Immune System of Bacteria!
Today is the last day for abstract submissions: sisb2026.rockefeller.edu
Thank you to Marraffini @naamaaviram.bsky.social Seed @jbdsf.bsky.social labs for organizing!
"The selfish ribosome" paper is now published in @plosbiology.org . Have a look! Many thanks to the editors and reviewers!
doi.org/10.1371/jour...
In this Essay, the evolution of life is construed as a ribosomal takeover, whereby the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensured the propagatio...
With Eugene Koonin, we propose a concept of “the selfish ribosome”, under which evolution of life is viewed as a ribosomal takeover, where the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensures the propagation of the ribosome. arxiv.org/abs/2602.23268
