A great failure of PEPFAR (among many successes) was not insisting on an RCT of switching vs not switching to DTG in a large cohort of African patients. Now we are stuck with observational evidence on the side-effects of INSTIs
www.thelancet.com/journals/lan...
Treatment regimens containing integrase strand-transfer inhibitors (INSTIs) are taken
lifelong by most people with HIV. The potency, tolerability, and high resistance barrier
of INSTIs make them the t...
