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@thenewsagents.co.uk Stopping all immigration to prevent crimes by immigrants (which I think is what the far right want) is akin to grounding all planes permanently to stop plane crashed.
Ever notices that RCTs of 'transformative' diagnostic tests almost never show benefit to patients. In Part 1 of 2, the Diagnostic Detective makes this case. In Part 2, I will attempt to explain why. open.substack.com/pub/thediagn...
Here I look at the missing information in the NEJM article about MiniDoc #tuberculosis thediagnosticdetective.substack.com/p/meeting-th...
A successful 4 month regimen with lots of cavitation is interesting. But why are drug companies so terrified of including real life HIV patients (CD4<350)? Has to be one regimen for all to be practical in low resource settings. www.thelancet.com/journals/lan...
3d
2mo
10d
#SouthAfrica’s rollout of #lenacapavir starts today. The twice-yearly long-acting injectable for #HIV prevention will be introduced at 360 government facilities nationwide, expanding prevention choice and marking an important step forward for the country’s HIV response. #RethinkRebuildRise
12d
This is excellent work once again. Well done Rachel and the rest of the team.
9d
A great failure of PEPFAR (among many successes) was not insisting on an RCT of switching vs not switching to DTG in a large cohort of African patients. Now we are stuck with observational evidence on the side-effects of INSTIs www.thelancet.com/journals/lan...
The Diagnostic Detective attempts to explain why study design is the biggest enemy of RCTs of diagnostic tests open.substack.com/pub/thediagn...
Tom Boyles
5d
Tom Boyles
2mo
Tom Boyles
Tom Boyles
1mo
IAS - the International AIDS Society
Tom Boyles
Tom Boyles
Tom Boyles
New: Risk & cause of death among people living with #HIV admitted to hospital Overall mortality remains unacceptably high (16%) & probably hasn’t changed since 2000 AIDS-related conditions (72%) esp. #TB (27%) main cause of death dx.doi.org/10.1002/jia2... @uofgshw.bsky.social #IDSky #TBSky 🧪🛟
5d
Peter MacPherson