Laboratory exploring the fibroblast's role in everything
UCSF Peng Lab
NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K+ T cells: Immunity www.cell.com/immunity/ful...
Excited to present Nancy's postoctoral work @ucsfaging.bsky.social @immunox.bsky.social defining the role of aging fibroblasts in driving inflammaging.
Sharing JinYoung's latest work @ucsfaging.bsky.social @ucsfstemcell.bsky.social in collaboration with @lindsaylafave.bsky.social on how senescent fibroblasts program tumor plasticity and metabolism. JY is starting her own lab at Inha University.
www.sciencedirect.com/science/arti...
Aging is accompanied by significant changes to the immune system. Allen et al. demonstrate
that age-related NF-κB activation in fibroblasts remodels the lung resident immune
system and promotes the em...
Senescence has been demonstrated to either inhibit or promote tumorigenesis. Resolving this paradox requires spatial mapping and functional characteri…