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by @jimpick.com
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Our latest research preprint demonstrating chemokine- based targeting of mRNA-LNPs to cytotoxic CD8 T cells and NK cells. A first in class gene therapy strategy. www.biorxiv.org/content/10.1...
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Selective in vivo reprogramming of cytotoxic effector CD8+ T (Teff) cells holds tremendous promise as a therapeutic tool but has not yet been accomplished. Here, we demonstrate that fractalkine-conjug...
www.biorxiv.org
In vivo reprogramming of cytotoxic effector CD8+ T cells via fractalkine-conjugated mRNA-LNP
Michael Betts