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Update: RareFold 🧬 Our AI framework for protein design with 29 noncanonical AAs now shows designed binders (linear + cyclic) are non-immunogenic in patient-derived assays — paving the way for safe next-gen peptide therapeutics. 👉https://www.biorxiv.org/content/10.1101/2025.05.19.654846v2
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Protein structure prediction and design have traditionally been limited to the 20 canonicalamino acids. Expanding this space to include noncanonical amino acids (NCAAs) offers newopportunities for pro...
RareFold: Structure prediction and design of proteins with noncanonical amino acids
Patrick Bryant